Associate Program Officer, Crohn's Disease

The Helmsley Charitable Trust seeks an Associate Program Officer (APO) to directly support the Crohn’s Disease Program Director and Officers. The APO will be responsible for administration of approximately one-third of the portfolio of funded projects, as well as helping to identify and develop new initiatives focusing on prevention and diagnostics of Crohn’s disease.

The APO will help manage administrative components of the grantmaking process, especially tasks associated with managing grant life-cycles; tracking program budgets and periodically reconciling with parallel systems; ensuring accurate payment and accounting of grants; helping to plan and execute complex program–related meetings; and maintaining positive and proactive communication with grantees. In addition to program administration, the APO will be expected to engage in substantive programmatic support to the portfolio through the following: review and response to proposals; conduct due diligence tasks for potential grants; managing and writing grant recommendations; monitoring the progress of existing grantees; and research in support of new strategy development. The APO will serve as a point of contact for applicants and grantees. Travel will be required.

The Crohn’s Disease Program, which made its first grant in 2009, is committed to finding a cure, and until then to improving quality of life and care and finding better treatments for Crohn’s disease. The program has made significant investments in research on the human genetics of Crohn's disease and understanding the human microbiome as it relates to Crohn's, as well as supporting numerous efforts to pursue transformative approaches to understanding and treating Crohn's. Seven consortia have been funded, significant intramural research programs are being supported at major scientific organizations, and the program is providing significant support for new ways to use technology and bioinformatics to study and treat Crohn's disease. To date, the program, which has rapidly become the largest private foundation funder in Crohn’s disease, has awarded over $183 million to scientists and clinicians across the globe.

  • Ensure timely and effective grants management processes; 
  • Assist Program Officer and other team members with grants process, which includes working with applicants to prepare proposals and project budgets as well as helping to analyze project proposals for review by the Program Director, CEO, and the Board of Trustees; 
  • Respond to inquiries from a wide range of constituencies, handling declinations and other correspondence as necessary; 
  • Research and write reports on selected areas of program interest. Summarize new trends, studies and initiatives for program staff;
  • Assist in the planning and execution of complex events and travel;
  • Meet with members of the foundation, for-profit, and nonprofit community about prospective projects; 
  • Represent Helmsley at conferences and site visits; 
  • Collaborate with colleagues in cooperative approaches to grantmaking;
  • Assist with the development of outcomes, metrics, and systems for collecting data and measuring the impact of the grant portfolio; 
  • Work with grantees to track progress on grants; and 
  • Administrative responsibilities related to the above and to other areas as needed.
  • MA/MS or higher degree required; public health policy or science research experience helpful;
  • Experience with grantmaking, preferably with multiyear awards programs preferred; 
  • Background in the nonprofit or foundation sectors preferred; 
  • Experience and interest in administration of medical and scientific research preferred. Experience in IBD and Crohn’s disease is preferred;
  • Must be organized, detail-oriented, and have strong interpersonal and communication skills;
  • Must demonstrate exceptional capacity in written and oral presentation;
  • Proficiency in Microsoft Word, Excel, PowerPoint, and Outlook;
  • Demonstrated ability to exercise independent judgment and initiative, prioritize and accurately complete multiple tasks, and work under deadlines;
  • Experience and desire to work in a team-oriented environment;
  • Able to maintain confidentiality of information; and 
  • A strong team player with a diplomatic, professional manner.

The position is based at Helmsley’s main office in New York City. Send a cover letter, resume (in Word or PDF format), and a brief writing sample to The writing sample must be an actual document you prepared in a professional context. Include “Associate Program Officer – Crohn's Disease Program” in the subject line. Only those selected for an interview will be contacted.


The Leona M. and Harry B. Helmsley Charitable Trust aspires to improve lives by supporting exceptional efforts in the U.S. and around the world in health and select place-based initiatives. Since beginning active grantmaking in 2008, Helmsley has committed more than $1.5 billion for a wide range of charitable purposes. Learn more about Helmsley at

The above statements are intended to describe the general nature and level of work being performed by the incumbent(s) of this job.  They are not intended to be an exhaustive list of all responsibilities and activities required for the position.  Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.