Salk Scientists Find 'Secret Sauce' for Personalized, Functional Insulin-Producing Cells

Salk scientists have successfully improved the ability to generate patient-derived, sugar-responsive cells that resemble pancreatic beta cells. These cells have the potential to be developed into therapies to treat type 1 and type 2 diabetes.

For over a decade, researchers have struggled to make human beta-like cells that are fully mature and functional. In this breakthrough, scientists at Salk discovered a switch that can be used in the laboratory dish to create more mature beta-like cells. The study’s findings, published in Cell Metabolism, offer new hope for diabetes therapy.