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Board of Trustees of the Leland Stanford Junior University


Date of Award

10.09.2024

Program

Therapeutics

Amount

$2,034,990.00

Term of Grant

36 months

Project Title

Determining the Therapeutic Potential of Statins on Stricturing Crohn's Disease

Project Description

Current CD therapeutics do not address the fibrosis underlying stricture formation. Statins are known to have anti-inflammatory and anti-fibrotic effects, and their repurposing for use in CD would expedite the drug development process. This project will establish the efficacy of statins to prevent stricture recurrence and expand the growing evidence for further therapeutic development.