Cedars-Sinai Medical Center

Date of Award

08.05.2026

Program

Prevention

Amount

$2,200,000.00

Term of Grant

30 months

Project Title

Underlying Mechanisms and Clinical Utility of Anti-GM-CSF Antibodies in Crohn's Disease (CD) Across Diverse Populations

Project Description

The overall goal of this proposal is to determine mechanisms underlying the development of anti-GM-CSF autoantibodies in Crohn's disease and validate their utility as early prognostic biomarkers for disease progression across ancestrally diverse population.