Chancellor Masters & Scholars Of The University Of Oxford

Date of Award

12.20.2022

Program

Therapeutics

Amount

$474,279.00

Term of Grant

30 months

Project Title

Interrogating the mechanism of hypersensitivity to antibody-based drugs for development of a novel anti-TNF biologic for Crohn's disease

Project Description

This project aims to identify the regions of the anti-TNF molecule that activate the immune system, allowing for the design of potential new anti-TNF drugs that will maintain their effectiveness over time.