Children’s Hospital Corporation

Date of Award

01.12.2026

Program

Therapeutics

Amount

$1,980,000.00

Term of Grant

36 months

Project Title

IL23R-Base-Edited Autologous HSC Therapy for Refractory Crohn's Disease

Project Description

This project aims to develop and validate a gene editing tool that can be used to modify patient's blood cells to reduce inflammatory signaling and reset the immune system.