Mass General Brigham for the Massachusetts General Hospital


Date of Award

07.08.2020

Program

Crohn's Disease, Prevention

Amount

$1,618,015

Term of Grant

36 months

Project Title

Crohn's Disease in South Asians: Defining disease biology for prevention and better treatment

Project Description

Previously considered to affect only individuals of European ancestry, Crohn’s disease has been emerging rapidly in newly industrialized nations. The fastest rise in incidence of CD is in Asia, with the highest regional prevalence in India. This study will assemble a unique international cohort of immigrant and native South Asian CD patients to identify characteristics of CD that are unique to SA patients and the environmental triggers in Western culture that contribute to the rise in incidence of CD in the developing world.