Massachusetts Institute of Technology

Date of Award

02.12.2019

Program

Diagnostics

Amount

$1,774,790.00

Term of Grant

36 months

Project Title

Implantable depots and fibers for early detection and treatment of peri-anastomotic inflammation in Crohn's disease

Project Description

Post-surgical anastomotic complications are significantly elevated in CD patients. A timely diagnosis is in critical need for early detection of abnormal, chronic inflammation, bacterial leakage, and subsequent induction of sepsis. If successful, this project will result in the development of materials that will allow for the early and non-invasive detection of anastomotic complications with the required properties to allow clinical testing in CD patients and minimize recurrence of the disease.