The Cleveland Clinic Foundation

Date of Award

02.09.2022

Program

Crohn's Disease, Diagnostics

Amount

$3,485,075

Term of Grant

36 months

Project Title

Development of a next-generation biomarker tool to accelerate the development of effective anti-fibrotic therapies

Project Description

The overall goal of this proposal is to develop and validate an intestinal mucosal and imaging biomarker for stricturing small bowel CD as a critical tool to measure the severity of the fibrotic process in CD strictures and support the development of anti-fibrotic therapies.