The University of Chicago


Date of Award

01.11.2018

Program

Crohn's Disease, Research Networks

Amount

$500,000

Term of Grant

18 months

Project Title

Aberrant tissue responses and microbial triggers that promote the development of UC pouchitis: Gathering clues to understand human inflammatory bowel diseases

Project Description

The pathogenesis of Crohn’s disease (CD) remains obscure and difficult to be studied throughout its entire course of development. This study aims to investigate pouchitis, a human model of CD, provide clinically relevant information regarding intestinal inflammation and identify host and microbial marker genes involved in disease onset.