Trustees Of The University Of Pennsylvania

Date of Award

09.08.2025

Program

Prevention

Amount

$4,573,615.00

Term of Grant

36 months

Project Title

Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients with Active Crohn's Disease: The PANDORA Study

Project Description

The project addresses critical gaps in Crohn's disease (CD) treatment, notably the limited effectiveness of current pharmacological therapies and the poor feasibility of existing dietary interventions like exclusive enteral nutrition (EEN). The grant will assess the effectiveness of partial enteral nutrition in combination with advanced therapies for treatment of CD.