Universitair Medisch Centrum Utrecht

Date of Award

02.09.2022

Program

Crohn's Disease, Prevention

Amount

$519,750

Term of Grant

36 months

Project Title

Epithelial-Based Diagnostics for Targeted Therapies of VEOIBD

Project Description

Functional characterization of intestinal epithelial cell-specific genes using patient-derived organoid models can lead to a better understanding of the genetic causes of VEO-IBD and can identify pathways to target with therapeutics not only for VEO-IBD but also for adult CD.