Universitair Medisch Centrum Utrecht
Date of Award
02.09.2022
Program
Crohn's Disease, Prevention
Amount
$519,750
Term of Grant
36 months
Project Title
Epithelial-Based Diagnostics for Targeted Therapies of VEOIBD
Project Description
Functional characterization of intestinal epithelial cell-specific genes using patient-derived organoid models can lead to a better understanding of the genetic causes of VEO-IBD and can identify pathways to target with therapeutics not only for VEO-IBD but also for adult CD.