University of Otago

Date of Award

10.06.2025

Program

Disease Management

Amount

$1,390,086.00

Term of Grant

36 months

Project Title

Evaluation of fecal myeloperoxidase as an accurate and rapid clinical test in Inflammatory Bowel Disease

Project Description

There is a need for new biomarkers that provide more precise monitoring of Crohn's disease (CD) activity—specifically, tools that are accurate, rapid, non-invasive, and cost-effective compared to currently available biomarkers. In this study, investigators will develop a simple and inexpensive point-of-care fMPO test and assess associations of faecal myeloperoxidase (fMPO) with endoscopic CD activity in a global cohort of patients with IBD. Prospectively assess the performance of fMPO to detect CD in patients referred for colonoscopy for chronic diarrhoea and for longitudinal outcomes in those diagnosed with CD.